METHODS AND COMPOSITIONS FOR DETECTION OF HPV DNA AND DIAGNOSIS AND MONITORING HPV-ASSOCIATED CANCERS

摘要

The present invention provides methods and compositions for the detection of HPV DNA in patient samples with high sensitivity and specificity. Such methods are useful in screening for HPV-associated malignancies. In some embodiments the present invention provides methods and compositions for the detection of HPV16, HPV33 and/or HP VI 8 DNA. In some embodiments the present invention provides methods and compositions for the detection of HPV DNA from squamous cell carcinomas, such as oropharyngeal squamous cell carcinomas and anal squamous cell carcinomas.