首页>
外国专利>
Orally dissolving melatonin formulation with acidifying agent that renders melatonin soluble in saliva
Orally dissolving melatonin formulation with acidifying agent that renders melatonin soluble in saliva
展开▼
机译:用酸化剂口服溶解褪黑激素制剂,使褪黑激素可溶于唾液
展开▼
页面导航
摘要
著录项
相似文献
摘要
A composition includes a pharmaceutical dosage form configured to dinsintegrate in saliva and maintain a pH of 4 or less within the saliva during the time the dosage form is dissolving therein. The dosage form includes a therapeutically effective amount of melatonin in a carrier matrix, a disintegrant, and a sufficient amount of acid to impart the pH to the saliva. The amount of disintegrant is sufficient to cause the dosage form to completely disintegrate in the saliva within ten minutes from contacting the saliva.
展开▼