USE OF A CD4/CD8 BISPECIFIC ANTIBODY FOR THE TREATMENT OF AUTOIMMUNE/INFLAMMATORY DISORDERS

摘要

The present disclosure is directed to bispecific antibodies binding to CD4 and CDS, and their use in treating autoimmune/inflammatory diseases. Specifically, the disclosure provides methods of treating a T cell mediated autoimmune/inflammatory disease in a subject comprising providing a bispecific antibody or antibody fragment having binding specificity for CD4 and CDS to said subject, wherein said autoimmune/inflammatory disease is not diabetes. Further disclosed are complementary determining regions (CDRs) sequences of bispecific antibodies.