Compositions and methods for decolonizing antibotic-resistant bacteria in the gut

摘要

The present invention relates to, in part, compositions and methods for delivery of novel mixtures of bacterial strains for the decolonization and/or eradication of various pathogenic bacteria and, particularly, antibiotic-resistant bacteria (ARB). The present invention comprises a pharmaceutical composition comprising a bacterial mixture comprising a 16S rRNA sequence that is greater than about 97% identical to the 16S rRNA sequence of any one of the operational taxonomic units (OTUs) recited in Table 5 and/or to the 16S rRNA sequence of any one OTU of a genus recited in Table 6. The present invention provides a method for treating an infection by one or more pathogens, comprising administering to a subject in need thereof an effective amount of the pharmaceutical composition.