首页>
外国专利>
Modifying the specificity of non-coding RNA molecules for silencing gene expression in eukaryotic cells
Modifying the specificity of non-coding RNA molecules for silencing gene expression in eukaryotic cells
展开▼
机译:修改非编码RNA分子的特异性以沉默真核细胞中的基因表达
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method of modifying a gene encoding or processed into a non-coding RNA molecule having no RNA silencing activity in a eukaryotic cell, with the proviso that said eukaryotic cell is not a plant cell, is disclosed. The method comprising introducing into the eukaryotic cell a DNA editing agent conferring a silencing specificity of said non-coding RNA molecule towards a target RNA of interest. A method of modifying a gene encoding or processed into a RNA silencing molecule to a target RNA in a eukaryotic cell is also disclosed. Methods of disease prevention and treatment, methods of inducing cell apoptosis and methods of generating a eukaryotic non-human organism are also disclosed.
展开▼