Genetic knockouts in Wood-Ljungdahl microorganisms

摘要

The invention provides genetically engineered Wood-Ljungdahl microorganisms comprising one or more disrupted genes to strategically divert carbon flux away from nonessential or undesirable products and towards products of interest. The expression strategies of the invention enable the production of useful fuels and chemicals from gaseous substrates, such as carbon monoxide, carbon dioxide, and/or hydrogen.