首页> 外国专利> Enhancer for T-cells or B-cells having memory function, malignant tumor recurrence inhibitor, and inducer for inducing memory function in T-cells or B-cells

Enhancer for T-cells or B-cells having memory function, malignant tumor recurrence inhibitor, and inducer for inducing memory function in T-cells or B-cells

机译:具有记忆功能的T细胞或B细胞的增强剂,恶性肿瘤复发抑制剂和诱导T细胞或B细胞中的记忆功能的诱导剂

摘要

The purpose of the present invention is to provide, in order to continue the rejection of malignant tumors over a long period of time, an enhancer for endogenous T-cells or B-cells having a memory function, and a malignant tumor recurrence inhibitor. The present invention involves preparing: an enhancer for subject T-cells or B-cells having a memory function, said enhancer including a nucleic acid transportation medium, a nucleic acid encoding interleukin 7 (IL-7) and a nucleic acid encoding chemokine (C-C motif) ligand 19 (CCL 19); an inducer which induces the memory function in the T-cells or B-cells in a subject; and a malignant tumor recurrence inhibitor which includes a nucleic acid transport medium, a nucleic acid encoding interleukin 7 (IL-7) and a nucleic acid encoding CCL19.
机译:本发明的目的是为了长期持续地排斥恶性肿瘤,提供具有记忆功能的内源性T细胞或B细胞的增强剂,以及恶性肿瘤复发抑制剂。本发明涉及制备:用于具有记忆功能的主题T细胞或B细胞的增强子,所述增强子包括核酸转运介质,编码白介素7(IL-7)的核酸和编码趋化因子(CC)的核酸。基序)配体19(CCL 19);在受试者的T细胞或B细胞中诱导记忆功能的诱导剂;恶性肿瘤复发抑制剂,其包括核酸转运介质,编码白介素7(IL-7)的核酸和编码CCL19的核酸。

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