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A functional polypeptide and its application thereof in preparing medicament for preventing and treating pulmonary fibrosis

机译:功能多肽及其在制备预防和治疗肺纤维化药物中的应用

摘要

#$%^&*AU2018353935B220200514.pdf#####ABSTRACT The present invention discloses a functional polypeptide which is 1) a polypeptide having the amino acid sequence of SEQ ID No. 1; or 2) a polypeptide having a substitution or deletion or addition of one or several amino acids from the sequence shown in SEQ ID No. 1 that has the same or similar function. The invention also discloses the utility of the described functional polypeptide. The functional polypeptide of the present invention can significantly inhibit bleomycin-induced pulmonary fibrosis formation and has a remarkable effect of preventing and treating pulmonary fibrosis.
机译:#$%^&* AU2018353935B220200514.pdf #####抽象本发明公开了一种功能性多肽,其为:1)多肽具有SEQ ID No.1的氨基酸序列;或2)具有从序列中取代或缺失或添加一个或几个氨基酸具有相同或相似功能的SEQ ID No.1所示。本发明也公开了所述功能多肽的用途。功能性本发明的多肽可显着抑制博来霉素诱导的肺纤维化形成并具有明显的防治作用肺纤维化。

著录项

  • 公开/公告号AU2018353935B2

    专利类型

  • 公开/公告日2020-05-14

    原文格式PDF

  • 申请/专利权人 GUANGDONG MEDICAL UNIVERSITY;

    申请/专利号AU20180353935

  • 发明设计人 ZHANG HAITAO;YU HUAJUN;WU JUN;LUO HUI;

    申请日2018-06-16

  • 分类号A61K31/4418;A61K38/10;A61P11;

  • 国家 AU

  • 入库时间 2022-08-21 11:12:22

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