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Triazacyclododecansulfonamide ('TCD')-based protein secretion inhibitors
Triazacyclododecansulfonamide ('TCD')-based protein secretion inhibitors
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机译:基于三氮杂十二烷基磺酰胺(“ TCD”)的蛋白质分泌抑制剂
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摘要
Provided herein are triazacyclododecansulfonamide ("TCD")-based protein secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same. For example, provided herein are compounds of Formula (I) and pharmaceutically acceptable salts and compositions including the same. The compounds disclosed herein may be used, for example, in the treatment of diseases including inflammation and/or cancer.
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