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Use of histone modifiers to reprogram effector T cells
Use of histone modifiers to reprogram effector T cells
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机译:使用组蛋白修饰剂重编程效应T细胞
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摘要
The present disclosure provides methods for re-programming effector T cells to a central memory phenotype comprising culturing the effector T cells with a histone deacetylase inhibitor (HDACi) and IL-21. Further provided are methods of treating cancer comprising administering the central memory T cells.
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