Disclosed herein is anticancer composition comprising an anti-cancer agent and poly(lactic-co-glycolic acid) (PLGA) carrier thereof. Further disclosed herein is a method for treating a breast disorder in a subject in need thereof, comprising administering to the breast of a subject via an intraductal injection an effective amount of a composition comprising a therapeutic agent and a PLGA carrier thereof. In some aspects the carrier is a micro sphere.
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