BIOMARKER FOR DIAGNOSIS OR PROGNOSIS PREDICTION OF LIVER CANCER METASTASIS AND USE THEREOF

摘要

The present invention relates to a biomarker for diagnosis or prognosis prediction of liver cancer metastasis and a use thereof and, more particularly, to a biomarker comprising exosomal miR-125b for diagnosis or prognosis prediction of liver cancer metastasis and a use thereof. The miRNA according to the present invention exhibits an expression behavior specific for patients with liver metastases and as such, can be used as a biomarker for diagnosing liver cancer metastasis. In addition, the miRNA can be used as a factor for predicting the prognosis of liver cancer metastasis and thus is applicable to a personalized medicine for liver cancer according to therapy determination and prognosis prediction for the patients.