首页> 外国专利> 4,5,6,7-TETRAHYDRO-L-BENZOTHIOPHENE MODULATORS OF RETINOIC ACID RECEPTOR RELATED (RAR) ORPHAN NUCLEAR RECEPTORS (RORS)

4,5,6,7-TETRAHYDRO-L-BENZOTHIOPHENE MODULATORS OF RETINOIC ACID RECEPTOR RELATED (RAR) ORPHAN NUCLEAR RECEPTORS (RORS)

机译:维甲酸受体相关(RAR)或潘汉核受体(RAR)的4,5,6,7-四氢-L-苯并噻吩调节剂

摘要

The invention encompasses the novel class of compounds represented by the Formula (I), (II), (III) and (IV) below, which are modulators of RORγt:. The invention also encompasses pharmaceutical compositions which include the compounds shown above and methods of treating or preventing autoimmune diseases and antibody mediated rejection in a patient in need thereof.
机译:本发明包括由下式(I),(II),(III)和(IV)表示的新型化合物,它们是RORγt的调节剂。本发明还包括药物组合物,其包括上述化合物以及在需要其的患者中治疗或预防自身免疫性疾病和抗体介导的排斥的方法。

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