OSTEOBLASTS DERIVED FROM ORAL NEUROECTODERMAL STEM CELLS AND THEIR USE IN JAW REPAIR

摘要

The present invention concerns a method for inducing differentiation of neuroectodermal oral stem cells, in particular from gingival tissue (GSCs), into osteoblasts by culturing them in an optimal serum-free medium supplemented by necessary components such as platelet lysate, growth hormone, heparin, and/or growth factors. The invention method provides osteoblasts for cell therapy, particularly for the restoration of bone defects in maxillary bones.