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CHROMENIC PHYTOCANNABINOIDS, THEIR SYNTHESIS AND USE IN TREATMENT OR PREVENTION OF DISEASE

机译:铬类植物大麻素及其合成及其在疾病预防或治疗中的用途

摘要

The present invention relates to a compound of the formula (I) or a solvate or co-crystal thereof (I) wherein: - R is selected from the group consisting of: a C1-C6 alkyl, a C2-C8 alkenyl moiety, a C4-C12 dienyl or a C6-C18 trienyl moiety; - R1 is a C1-C6 alkyl moiety; - R2 is selected from the group consisting of: H and a C1-C6 alkyl moiety; - R3 is selected from the group consisting of: H and a C1-C6 alkyl moiety; - R4 is selected from the group consisting of: H, a C1-C6 alkyl moiety and a benzyl moiety. The present invention also relates to a process for producing said compound of the formula (I), or a solvate or co-crystal thereof, as well as a pharmaceutical composition comprising said compound of the formula (I), or a solvate or co-crystal thereof and at least one excipient. The present invention also relates to a compound of the formula (I), or a solvate or co-crystal thereof, for use in the treatment or prevention of a disease or condition.
机译:本发明涉及式(I)化合物或其溶剂化物或共结晶(I),其中:-R选自:C 1 -C 6 烷基,C 2 -C 8 烯基部分,C 4 -C 12 二烯基或C 6 -C 18 三烯基部分; -R 1 是C 1 -C 6 烷基部分; -R 2 选自:H和C 1 -C 6 烷基部分; -R 3 选自:H和C 1 -C 6 烷基部分; -R 4 选自:H,C 1 -C 6 烷基部分和苄基部分。本发明还涉及制备所述式(I)化合物或其溶剂化物或共晶体的方法,以及包含所述式(I)化合物或溶剂化物或共晶体的药物组合物。其晶体和至少一种赋形剂。本发明还涉及用于治疗或预防疾病或病症的式(I)化合物或其溶剂化物或共结晶。

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