APPLICATION OF HUMAN ENDOMETRIUM ENDOTHELIAL PROJENITOR CELLS IN IMPROVING CARDIOMYOCYTE DAMAGE

摘要

The present invention relates to an application of human endometrium endothelial progenitor cells in improving cardiomyocyte damage. Resuspending human endometrium endothelial progenitor cells in a phosphate buffer saline PBS to form a stem cell preparation, injecting locally into a damaged portion of the heart of a model rat, performing a heart color ultrasound to observe changes in heart function, performing positron emission tomography - computed tomography (PET-CT) to observe cardiomyocyte activity and energy metabolism, performing Masson staining to observe a degree of fibrosis, and displaying a comparison to human mesenchymal stem cells; human endometrium endothelial progenitor cells have better effects on improving cardiomyocyte activity, energy metabolism, heart fibrosis, etc., and ultimately achieve the aim of repairing a damaged heart. The human endometrium endothelial progenitor cell preparation provided in the present invention may act as a medication for improving damaged cardiomyocyte activity and function, for application to diseases of the cardiovascular system.