SYSTEMIC SCLEROSIS DISEASE MODEL AND USE THEREOF

摘要

The present invention relates to: a method for developing a systemic sclerosis disease model by using keratinocytes and fibroblasts differentiated from induced pluripotent stem cells derived from patients with systemic sclerosis; a systemic sclerosis disease model developed thereby; and a method for screening for systemic sclerosis therapeutic agent by using same. A systemic sclerosis disease model developed by the development method can be effectively usable in the prevention or treatment of systemic sclerosis.