首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING GLOMERULAR DISEASES, CONTAINING GINSENOSIDE RG3 OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENT

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING GLOMERULAR DISEASES, CONTAINING GINSENOSIDE RG3 OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AS ACTIVE INGREDIENT

机译:预防或治疗肾小球疾病,包含人参皂苷RG3或作为活性成分的药学上可接受的盐的药物组合物

摘要

The present invention pertains to a pharmaceutical composition for preventing or treating glomerular diseases, the composition containing ginsenoside Rg3 or a pharmaceutically acceptable salt thereof as an active ingredient. It was found that the ginsenoside Rg3 of the present invention can prevent damage to human podocytes by inhibiting apoptosis and inflammatory response caused by the ER stress of human podocytes. Thus, the ginsenoside Rg3 and a pharmaceutically acceptable salt thereof can be used as an active ingredient of a composition for treating or preventing glomerular diseases.
机译:本发明涉及用于预防或治疗肾小球疾病的药物组合物,该组合物包含人参皂苷Rg3或其药学上可接受的盐作为活性成分。发现本发明的人参皂苷Rg3可以通过抑制由人足细胞的ER应激引起的凋亡和炎症反应来防止对人足细胞的损害。因此,人参皂苷Rg3及其药学上可接受的盐可用作治疗或预防肾小球疾病的组合物的活性成分。

著录项

  • 公开/公告号WO2020145416A1

    专利类型

  • 公开/公告日2020-07-16

    原文格式PDF

  • 申请/专利权人 JEON JIN SEOK;

    申请/专利号WO2019KR00217

  • 发明设计人 JEON JIN SEOK;

    申请日2019-01-07

  • 分类号A61K31/704;A61P13/12;A23L33/125;

  • 国家 WO

  • 入库时间 2022-08-21 11:10:12

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