首页> 外国专利> METHOD FOR ENHANCING EUSTACHIAN TUBE PATENCY AND TREATMENT OF OTITIS MEDIA

METHOD FOR ENHANCING EUSTACHIAN TUBE PATENCY AND TREATMENT OF OTITIS MEDIA

机译:增强咽鼓管声纳和治疗中耳炎的方法

摘要

A method of increasing eustachian tube patency in human patients is disclosed wherein a eustachian tube targeting nasal administration device is utilized to deliver a surfactant/propellant mixture to the nasopharyngeal stoma of the auditory tube. The targeting capability of the administration device obviates the need for a spreading agent that would otherwise be required to enable at least a portion of surfactant to reach the eustachian tube orifice. More specifically, the non-targeting, indiscriminate delivery provided by nasal administration devices of the past required surfactant to spread over non-targeted tissue it was inadvertently applied to in order to reach the eustachian tube stoma. In addition, a method for treatment of otitis media is disclosed utilizing, in some preferred embodiments, a therapeutically active agent.
机译:公开了一种增加人类患者的咽鼓管通畅性的方法,其中利用咽鼓管靶向鼻腔给药装置将表面活性剂/推进剂混合物递送至听觉管的鼻咽造口。给药装置的靶向能力消除了对铺展剂的需要,否则将需要铺展剂以使至少一部分表面活性剂到达咽鼓管孔。更具体地,由过去的鼻腔给药装置提供的非靶向的,不加区别的递送需要表面活性剂在其非靶向组织上的分布而被不经意地施加以达到咽鼓管造口。另外,在一些优选的实施方案中,公开了一种用于治疗中耳炎的方法。

著录项

  • 公开/公告号WO2020154074A1

    专利类型

  • 公开/公告日2020-07-30

    原文格式PDF

  • 申请/专利权人 ALRICH PARTNERS INC.;

    申请/专利号WO2020US00002

  • 发明设计人 NYIRUCZ ALEX;STRAUSS RICHARD;MAUTONE ALAN;

    申请日2020-01-07

  • 分类号A61M11/02;A61M15;A61M15/08;A61K31/137;A61K31/43;A61K31/573;A61K31/685;A61K31/7048;A61K45;A61K45/06;A61K47/14;A61K47/24;A61K47/26;A61K47/42;A61K9;A61K9/12;A61K9/127;A61K9/14;A61P27/16;

  • 国家 WO

  • 入库时间 2022-08-21 11:10:01

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