DETECTION OF BRAIN-DERIVED DEBRIS IN RECIRCULATING PHAGOCYTES

摘要

Methods for detecting or monitoring active disease processes, such as neurodegenerative disease processes or central nervous system damage related to Multiple Sclerosis, Alzheimer's disease, Parkinson's disease, mild cognitive impairment, traumatic brain injury, amyotrophic lateral sclerosis, or the like, wherein biomarkers associated with said disease processes are detected in circulating phagocytes outside of the central nervous system, The ability to detect active disease in patients may be useful for building cohorts of patients for drug trials, wherein only patients with active disease.