A method for producing a poultry litter-based fertilizer having an enhanced nitrogen level, enhanced ratio of nitrogen to phosphorous, and increased sulfur by a) supplying poultry litter to a rotating rotary drum, b) adding acid or a source of acid to the rotating rotary drum, wherein acid reacts with the poultry litter to form an acidified mixture, c) adding ammonia or a source of ammonia to the rotating rotary drum, wherein ammonia reacts with the acidified mixture to produce an ammoniated mixture containing an ammonium salt and heat, d) drying and cooling the ammoniated product to form a dried, cooled product in a free-flowing semi-solid or solid form, repeating the steps b) through d) until a desired nitrogen content is reached in the dried, cooled product, adjusting the pH in at least one step b) to destroy pathogens, weed seeds, drugs, hormones, and/or antibiotics present in the poultry litter.
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