METHODS AND COMPOSITIONS FOR TREATING CANCER BY TARGETING FATP2 AND MYELOID DERIVED SUPPRESSOR CELLS

摘要

A method of treating cancer in a subject in need thereof is provided. The method includes administering an agent that inhibits, decreases, deletes or downregulates FATP2. In one embodiment, the method includes administering a checkpoint inhibitor. Also provided are methods of decreasing MDSCs and MDSC immune-suppressive activity in a subject in need thereof.