Disclosed is a four-channel LED light source controller based on USB communication. The controller comprises: four LED light source interfaces (104, 107, 110, 113) for LED light source access, four channel power source interfaces (102, 105, 108, 111) for light source voltage access and four constant-current source circuits (103, 106, 109, 112), wherein each LED light source interface (104, 107, 110, 113) is connected to a constant-current source circuit (103, 106, 109, 112); the constant-current source circuits (103, 106, 109, 112) are connected to a CPU (101); each constant-current source circuit (103, 106, 109, 112) is connected to a channel power source interface (102, 105, 108, 111); and a TRIG interface (116) is connected to the CPU (101) by means of a TRIG conversion circuit (117).
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