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MICRORNA REGULATORY NETWORK AS BIOMARKERS OF SEIZURE IN PATIENTS WITH SPONTANEOUS INTRACEREBRAL HEMORRHAGE
MICRORNA REGULATORY NETWORK AS BIOMARKERS OF SEIZURE IN PATIENTS WITH SPONTANEOUS INTRACEREBRAL HEMORRHAGE
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机译:微小RNA调节网络作为自发性脑室内出血患者的镇定生物标志物
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摘要
A method of predicting seizure in a subject that has had an intracerebral hemorrhage, comprising: measuring at least one of miRNA listed in Tables 1A, 1B, 1C and 6-8 in a sample obtained from a subject, wherein the at least one of miRNA comprises at least one of hsa-miR-4325, hsa-miR-181a-5p, hsa-miR-1180-3p, and miR-4317 wherein down regulation of hsa-miR-4325 or hsa-miR-4317 relative to a control indicates the subject will exhibit seizures and wherein upregulation of hsa-miR-181a-5p and hsa-miR-1180-3p, relative to a control indicates the subject will exhibit seizures.
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