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AMINO ACID MODIFIED LIGNIN BROAD-SPECTRUM ANTIBACTERIAL AGENT AND PREPARATION METHOD AND APPLICATION THEREOF

机译:氨基酸改性木质素广谱抗菌剂及其制备方法和应用

摘要

The present invention belongs to the technical field of natural polymer antibacterial agents; disclosed are an amino acid modified lignin broad-spectrum antibacterial agent and preparation method and application thereof. The preparation method comprises the following steps: in an alkaline solution containing 5-50 parts by weight of lignin, adding 1-5 parts by weight of aldehyde and 1-5 parts by weight of amino acid; after heating and reacting at 40-120°C for 1-6 h, obtaining amino acid modified lignin broad-spectrum antibacterial agent. Also provided is an amino acid modified lignin broad-spectrum antibacterial agent prepared by the described method. In the preparation method, the active amino acid component modified lignin in the natural antibacterial peptide is used to obtain an amino acid modified lignin broad-spectrum antibacterial agent, effectively enhancing the antibacterial activity of the lignin and causing same to have high antibacterial activity and antibacterial performance superior to that of lignin; at the same time, the invention has an inhibitory effect on Gram-positive and -negative bacteria, and has broad-spectrum antibacterial properties; also, its toxicity is low, it has good biocompatibility, and it has enormous prospects for application in the fields of biomedicine, food, and cosmetics.
机译:本发明属于天然高分子抗菌剂技术领域。公开了一种氨基酸修饰的木质素广谱抗菌剂及其制备方法和应用。该制备方法包括以下步骤:在含有5-50重量份木质素的碱性溶液中,加入1-5重量份的醛和1-5重量份的氨基酸;于40-120℃加热反应1-6小时后,得到氨基酸修饰的木质素广谱抗菌剂。还提供了通过所述方法制备的氨基酸改性的木质素广谱抗菌剂。在制备方法中,天然抗菌肽中的活性氨基酸成分修饰的木质素用于获得氨基酸修饰的木质素广谱抗菌剂,有效增强了木质素的抗菌活性,使其具有较高的抗菌活性和抗菌性。性能优于木质素;同时,本发明对革兰氏阳性和阴性细菌具有抑制作用,并具有广谱抗菌特性。而且,它的毒性低,具有良好的生物相容性,在生物医学,食品和化妆品领域具有广阔的应用前景。

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