首页> 外国专利> COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASES USING CD9 AND METHOD FOR SCREENING THERAPEUTIC AGENT FOR NEURODEGENERATIVE DISEASES

COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASES USING CD9 AND METHOD FOR SCREENING THERAPEUTIC AGENT FOR NEURODEGENERATIVE DISEASES

机译:使用CD9预防或治疗神经退行性疾病的组合物以及筛选神经退行性疾病的治疗剂的方法

摘要

The present invention relates to a composition for the prevention or treatment of neurodegenerative diseases using CD9, and a method for screening a therapeutic agent for neurodegenerative diseases and, more specifically, to a pharmaceutical composition for the prevention or treatment of neurodegenerative diseases comprising, as an active ingredient, an inhibitor against the expression or activity of CD9 protein, and a method for screening a therapeutic agent for neurodegenerative diseases. A material for inhibiting the expression or activity of CD9 exhibits the effect of improving the memory of patients with neurodegenerative diseases, and thus can be effectively used in the development of a therapeutic agent for neurodegenerative diseases, and through assay of the expression level of CD9, candidate materials for the therapeutic agent for neurodegenerative diseases can be screened.
机译:本发明涉及使用CD9预防或治疗神经退行性疾病的组合物,以及用于筛选神经退行性疾病的治疗剂的方法,更具体地,涉及预防或治疗神经退行性疾病的药物组合物,其包含活性成分,针对CD9蛋白表达或活性的抑制剂以及筛选神经退行性疾病治疗剂的方法。用于抑制CD9表达或活性的材料具有改善神经退行性疾病患者记忆力的作用,因此可以有效地用于神经退行性疾病治疗剂的开发,以及通过检测CD9的表达水平,可以筛选神经退行性疾病治疗剂的候选材料。

著录项

  • 公开/公告号WO2020213982A1

    专利类型

  • 公开/公告日2020-10-22

    原文格式PDF

  • 申请/专利权人 HWANG JUNG HOO;

    申请/专利号WO2020KR05155

  • 发明设计人 HWANG JUNG HOO;

    申请日2020-04-17

  • 分类号A61K39/395;A61K31/7088;A61P25/28;G01N33/68;C12Q1/6883;

  • 国家 WO

  • 入库时间 2022-08-21 11:08:53

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