CGRP ANTAGONISTS FOR THE TREATMENT OF MEDICATION OVERUSE HEADACHE, POST-TRAUMATIC HEADACHE, POST-CONCUSSION SYNDROME AND VERTIGO

摘要

The application provides methods for treating, preventing, alleviating or reducing the frequency of occurrence of medication overuse headache, post-traumatic headache, post-concussion syndrome and vertigo in patients by the administration of calcitonin gene-related peptide (CGRP-antagonists). The CGRP-antagonists can be selected from ubrogepant or atogepant, or a pharmaceutically acceptable salt, ester or prodrug thereof. Anti-CGRP antibodies, such galcanezumab, fremanezumab, eptinezumab, and erenumab can also be used.