An application of serum exosome has_circ_0004771 in preparing a reagent for alcohol dependence syndrome diagnosis. The most significant circRNA, which has clear effectiveness when applied in clinical alcohol dependence (AD) detection, has been screened by studying changes in circRNA expression in serum exosomes of AD patients. The exosome hsa_circ_0004771 has high diagnostic value for AD, the expression level of the exosome is related to AD severity, and the exosome may be used as a marker for AD diagnosis and severity evaluation. The development and application of a serum circRNA marker and a diagnostic reagent kit may enable the diagnosis of AD to be easier and more convenient, in order to allow a clinician to quickly and accurately grasp the condition of a patient, lay a foundation for improving clinical treatment effects, and assist in the discovery of new small molecule drug targets with potential treatment value.
展开▼
