首页> 外国专利> BONE-SPECIFIC COMPLEX COMPRISING BONE CELL TRANSFORMATION RECOMBINANT PROTEIN AND BONE-TARGETING MOLECULE

BONE-SPECIFIC COMPLEX COMPRISING BONE CELL TRANSFORMATION RECOMBINANT PROTEIN AND BONE-TARGETING MOLECULE

机译:包含骨细胞转化重组蛋白和骨靶向分子的骨特异性复合物

摘要

The present invention relates to a bone-specific complex and can solve the stability problem of a viral carrier and foreign gene expression technology by inducing overexpression of targeted inherent genes without the influx of foreign genes. The present invention allows enhanced efficiency by stably labeling a targeted object and accurately confirming whether or not application is carried out to the targeted object, and thus can efficiently be applied to the field of developing a new protein-based drug technology requiring particular cell transformation such as osteoporosis and direct transdifferentiation.
机译:本发明涉及骨特异性复合物,并且可以通过诱导靶向内在基因的过表达而不引入外来基因来解决病毒载体和外来基因表达技术的稳定性问题。本发明通过稳定地标记目标对象并准确地确认是否对目标对象进行应用而提高了效率,因此可以有效地应用于开发需要特定细胞转化的基于蛋白质的新药物技术领域。如骨质疏松和直接转分化。

著录项

  • 公开/公告号WO2020218836A1

    专利类型

  • 公开/公告日2020-10-29

    原文格式PDF

  • 申请/专利权人 SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION;

    申请/专利号WO2020KR05353

  • 发明设计人 HWANG SUK-YEON;PARK GWANGLI;

    申请日2020-04-23

  • 分类号C07K14/47;C07K14/435;C07K19;C09K11/06;A61K49;

  • 国家 WO

  • 入库时间 2022-08-21 11:08:45

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