FUNCTIONAL COMPOSITION CONTAINING IMMORTALIZED STEM CELL-DERIVED EXOSOME-RICH CULTURE MEDIUM AND ROSEBUD EXTRACT AS ACTIVE INGREDIENTS

摘要

The present invention relates to a functional composition containing an immortalized stem cell-derived exosome-rich culture medium and rosebud extract as active ingredients. Specifically, the composition containing the immortalized stem cell-derived exosome-rich culture medium and the rosebud extract as active ingredients, according to the present invention, has excellent activity in inhibiting mast cell granule secretion, inhibiting immunoglobulin E (IgE) in serum, inhibiting histamines in serum, and improving itchiness, and is excellent in tyrosinase inhibitory activity and melanin production inhibitory activity, and thus can be used in the manufacture of a cosmetic composition having activity in atopic dermatitis improvement, skin wrinkle improvement, and whitening as well as can be usefully used in the manufacture of a pharmaceutical composition for the prevention or treatment of atopic dermatitis and pigmentation disorders.