首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MYOSITIS, COMPRISING ISOLATED MITOCHONDRIA AS ACTIVE INGREDIENT

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING MYOSITIS, COMPRISING ISOLATED MITOCHONDRIA AS ACTIVE INGREDIENT

机译:预防或治疗肌阵挛的药物组合物,包含孤立的线粒体作为有效成分

摘要

The present invention relates to a pharmaceutical composition for preventing or treating myositis and, more specifically, to a pharmaceutical composition for preventing or treating myositis, comprising mitochondria as an active ingredient. When administered to an entity suffering from myositis, the pharmaceutical composition comprising foreign mitochondria as an active ingredient, according to the present invention, can reduce infiltrative inflammatory cells among myocytes of the entity. Also, the pharmaceutical composition according to the present invention effectively suppresses the expression of IL-1β, TNF-α, and IL-6, which are inflammatory cytokines. Accordingly, the pharmaceutical composition according to the present invention can be beneficially used in the prevention or treatment of myositis.
机译:本发明涉及一种用于预防或治疗肌炎的药物组合物,更具体地说,涉及一种用于预防或治疗肌炎的药物组合物,其包含线粒体作为活性成分。当施用于患有肌炎的实体时,根据本发明的包含外来线粒体作为活性成分的药物组合物可以减少实体的肌细胞中的浸润性炎症细胞。另外,根据本发明的药物组合物有效地抑制了作为炎性细胞因子的IL-1β,TNF-α和IL-6的表达。因此,根据本发明的药物组合物可以有益地用于预防或治疗肌炎。

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