L- PHARMACEUTICAL FORMULATION INCLUDING AMORPHOUS DAPAGLIFLOZIN L-PROLINE AND PREPARATION METHOD THEREOF

摘要

The present invention provides a complex containing metformin and dapagliflozin L-proline. The present invention has an excellent dissolution rate and bioavailability, and has high stability of dapagliflozin, thereby being able to significantly improve the convenience of medication. In addition, the present invention can minimize side effects while maximizing the efficacy of dapagloflozin and metformin, and can significantly improve the convenience of medication for patients.