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Methods of treating or ameliorating metabolic disorders using binding proteins for gastric inhibitory peptide receptors (GIPR) in combination with GLP-1 agonists

机译:使用胃抑制肽受体结合蛋白(GIPR)结合GLP-1激动剂治疗或改善代谢异常的方法

摘要

Methods of treating metabolic diseases and disorders using antigen binding proteins specific for GIPR polypeptides are provided. In various embodiments, the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels, and diabetic neuropathy. In certain embodiments, the antigen binding protein is administered in combination with a GLP-1 receptor agonist.
机译:提供了使用对GIPR多肽具有特异性的抗原结合蛋白治疗代谢性疾病和病症的方法。在各种实施方案中,代谢疾病或病症是2型糖尿病,肥胖症,血脂异常,葡萄糖水平升高,胰​​岛素水平升高和糖尿病性神经病。在某些实施方案中,抗原结合蛋白与GLP-1受体激动剂组合施用。

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