NOVEL FLUORESCEIN DERIVATIVE COMPOUND, METHOD FOR MANUFACTURING SAME, AND METHOD FOR DETECTING ZINC (ZN^2+) ION USING SAME

摘要

The present invention provides a method for detecting zinc (Zn^2+) ions by synthesizing N-(3,6-dihydroxy-3-oxospyro[isoindoline-1,9-xanthene]-2-yl)-2-hydroxybenzamide, followed by using fluorescent organic nanoparticles obtained through a reprecipitation method. A novel fluorescein derivative compound, a manufacturing method thereof, and a method for detecting zinc ions using the same of the present invention exhibit a very low detection limit (0.0011 g/ml), are non-toxic, and can detect zinc ions in living cells, thereby being able to be usefully used in biomedical and environmental fields.;COPYRIGHT KIPO 2020