Methods of treating and / or preventing graft-versus-host disease and / or diffuse alveolar bleeding and / or venous occlusive disease associated with hematopoietic stem cell transplantation

摘要

In one aspect, the invention provides a method of inhibiting the effect of MASP-2-dependent complement activation in human subjects suffering from graft-versus-host disease and / or diffuse alveolar bleeding and / or venous occlusive disease associated with hematopoietic stem cell transplantation. . The method includes administering an effective amount of an MASP-2 inhibitor to inhibit MASP-2-dependent complement activation to a subject in need thereof.