Anti-B cell maturation antigen chimeric antigen receptor with human domain

摘要

The present invention relates to a chimeric antigen receptor (CAR) having antigen specificity for B cell maturation antigen (BCMA). The present invention also relates to nucleic acids, recombinant expression vectors, host cells, cell populations and pharmaceutical compositions related to CAR. The invention also relates to a method of treating or preventing cancer in a mammal.