首页> 外国专利> MICRORNA BIOMARKER FOR DIAGNOSING DIABETIC NEPHROPATHY AND USE THEREOF

MICRORNA BIOMARKER FOR DIAGNOSING DIABETIC NEPHROPATHY AND USE THEREOF

机译:微小RNA生物标记物用于诊断糖尿病性肾病及其用途

摘要

The present invention relates to a biomarker for diagnosing diabetic nephropathy and a use thereof and, more particularly, to a marker composition for diagnosing diabetic nephropathy comprising at least one selected from the group consisting of microRNA-642a (miR-642a), microRNA-1246 (miR-1246), microRNA-1255b (miR-1255b), and microRNA-5010 (miR-5010), a composition and a kit for diagnosing diabetic nephropathy comprising an agent for measuring an expression level of the miRNA, and a method for diagnosing diabetic nephropathy using the marker. According to the present invention, microRNAs specific to the presence of renal complications can be useful as a biomarker for diagnosing diabetic nephropathy and predicting a progress thereof.;COPYRIGHT KIPO 2020
机译:本发明涉及一种用于诊断糖尿病性肾病的生物标志物及其用途,更具体地,涉及一种用于诊断糖尿病性肾病的标志物组合物,其包含选自microRNA-642a(miR-642a),microRNA-1246中的至少一种。 (miR-1246),microRNA-1255b(miR-1255b)和microRNA-5010(miR-5010),用于诊断糖尿病性肾病的组合物和试剂盒,包括用于测量miRNA表达水平的试剂,以及用于使用标记物诊断糖尿病性肾病。根据本发明,对肾并发症存在特异性的微小RNA可用作诊断糖尿病性肾病并预测其进展的生物标记。COPYRIGHTKIPO 2020

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