COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING ATOPIC DERMATITIS CONTAINING APIUM GRAVEOLENS HYDROLYSATE AS ACTIVE INGREDIENT

摘要

The present invention relates to a composition for preventing, alleviating, or treating atopic dermatitis containing an Apium graveolens hydrolysate as an active ingredient. The acid hydrolysate of an Apium graveolens extract, an active ingredient of the present invention, inhibits the proliferation of spleen cells and inhibits the secretion of atopic-related factors (IL-4, IL-6, INF-, TNF-, IgE, and CCL17). In addition, compared to an Apium graveolens ethanol extract, the skin lesion improvement effect of an atopic dermatitis-induced animal model is superior, and the skin thickness and the concentration of IL-4 and IgE in the blood are significantly reduced. Therefore, the composition containing the acid hydrolysate of the Apium graveolens extract as an active ingredient of the present invention can be usefully used as a quasi-drug for atopic dermatitis, a health functional food for atopic patients, and a material for an atopic dermatitis medicine.;COPYRIGHT KIPO 2020