首页> 外国专利> -1 Tenoderasin-1 peptide isolated from Tenodera sinensis or antimicrobial antimycotic and antiinflammatory composition comprising it

-1 Tenoderasin-1 peptide isolated from Tenodera sinensis or antimicrobial antimycotic and antiinflammatory composition comprising it

机译:从中华绒螯蟹中分离的-1 Tenoderasin-1肽或包含它的抗菌抗真菌和抗炎组合物

摘要

The present invention relates to tenoderasin-1 peptide derived from Tenodera sinensis, and an antimicrobial, antimycotic, or anti-inflammatory composition comprising the same as an effective component. The tenoderasin-1 peptide according to the present invention has excellent antimicrobial or antimycotic effects against Staphylococcus aureus, Escherichia coli O157, Candida albicans, and the like, is capable of inhibiting the secretion of nitric oxide (NO), and is capable of suppressing the expression of IL-6, IL-1β, iNOS, COX-2, and the like, thereby being easily usable as a therapeutic agent for various inflammatory diseases.
机译:本发明涉及来源于中华绒螯蟹(Tenodera sinensis)的肌腱蛋白-1肽,以及包含其作为有效成分的抗微生物,抗真菌或抗炎组合物。根据本发明的tenoderasin-1肽对金黄色葡萄球菌,大肠杆菌O157,白色念珠菌等具有优异的抗微生物或抗真菌作用,能够抑制一氧化氮(NO)的分泌,并且能够抑制一氧化氮(NO)的分泌。 IL-6,IL-1β,iNOS,COX-2等的表达,因此容易用作各种炎性疾病的治疗剂。

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