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33- Novel 33-difluoroallylamine derivatives or its salt and pharmaceutical compositions comprising the same

机译:33-新型33-二氟烯丙胺衍生物或其盐和包含该衍生物的药物组合物

摘要

The present invention provides a 3,3-difluoroallylamine derivative or a pharmaceutically acceptable salt thereof, a method for preparing the same, a pharmaceutical composition comprising the same, and uses thereof. The 3,3-difluoroallylamine derivative or a pharmaceutically acceptable salt thereof has a selective inhibitory activity against VAP-1, and is useful for the treatment and prevention of non-alcoholic steatohepatitis (NASH), for example. Can be applied.
机译:本发明提供了3,3-二氟烯丙胺衍生物或其药学上可接受的盐,其制备方法,包含其的药物组合物及其用途。 3,3-二氟烯丙基胺衍生物或其药学上可接受的盐具有对VAP-1的选择性抑制活性,并且可用于例如治疗和预防非酒精性脂肪性肝炎(NASH)。可以申请。

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