Method of Synthesis for Mycophenolic Acid and Its Phenylsulfenyl and Phenylseleny Analogues

摘要

The present invention relates to a method for synthesizing mycophenolic acid, phenylsulfenyl and phenylselenyl derivatives thereof, and a novel phenylsulfenyl or phenylselenyl derivative compound of mycophenolic acid synthesized by the above synthesis method. The method for synthesizing the new mycophenolic acid of the present invention does not use a protecting group as compared with the conventional synthetic method, and the reaction step is simple and has a high yield. Therefore, the synthetic method of the present invention can be usefully used for high-yield mass production method of mycophenolic acid.