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Improved method for the synthesis of linker-drug vc-seco-DUBA

机译：接头-药物vc-seco-DUBA合成的改进方法

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摘要

The present invention is an improved method for the synthesis of a linker-drug vc- seco- DUBA and intermediates thereof, and the use of the improved method in a method for preparing an antibody-drug conjugate comprising a vc- seco- DUBA linker-drug. It is about.

机译：本发明是一种用于合成接头-药物vc- - DUBA及其中间体的改进方法，并且该改进方法在制备包含以下内容的抗体-药物缀合物的方法中的用途： vc- seco- DUBA链接器-药物。关于。 展开▼

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公开/公告号KR20200091431A

专利类型

公开/公告日2020-07-30

原文格式PDF

申请/专利权人 비온디스 비.브이.;
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申请/专利号KR20207018101

发明设计人 야노우셰크 블라디미르;카스 마틴;
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申请日2018-11-22

分类号C07D471/04;A61K47/68;A61P35;

国家 KR

入库时间 2022-08-21 11:06:17

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专利

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中文文献

1. 用于合成接头-药物VC-SECO-DUBA的改进方法 [P] . 中国专利： CN111556870A . 2020-08-18

2. 合成抗疟疾药物的改进方法 [P] . 中国专利： CN1865227B . 2012.05.09

3. IMPROVED METHOD FOR LINKER-DRUG SYNTHESIS VC-SECO-DUBA [P] . RU2020120838A . 2021-12-24

机译：改进的接头 - 药物合成VC-SECO-DUBA方法

4. Improved process for the synthesis of linker-drug vc-seco-DUBA [P] . AU2018371966A1 . 2020-06-18

机译：改进的连接子-药物vc-seco-DUBA的合成方法

5. IMPROVED PROCESS FOR THE SYNTHESIS OF LINKER-DRUG VC-SECO-DUBA [P] . CA3083169A1 . 2019-05-31

机译：链接器VC-SECO-DUBA的合成工艺改进

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