首页> 外国专利> Relapse Prediction Method for patient with breast cancer Using immune response differential gene expression Model

Relapse Prediction Method for patient with breast cancer Using immune response differential gene expression Model

机译:基于免疫反应差异基因表达模型的乳腺癌患者复发预测方法

摘要

The present invention relates to a method for predicting recurrence in breast cancer patients using an immunogene differential expression model. According to the present invention, the steps of collecting biopsy tissue from a breast cancer patient as a subject, obtaining information on a plurality of differentially expressed genes and expression levels from the biopsy tissue using an RNA extraction kit, and the plurality of differentially expressed genes And predicting the likelihood of recurrence of the subject by applying the expression level information for the pre-trained immunogene differential expression model. As described above, according to the present invention, the recurrence prediction method for breast cancer patients extracts genes differentially expressed among immune-related genes in breast cancer, and can predict recurrence from data with a small number of samples through the extracted differentially expressed genes. Immune gene differential expression models can be constructed. Therefore, it is possible to predict the recurrence of breast cancer patients with high accuracy at low cost.
机译:本发明涉及一种使用免疫基因差异表达模型预测乳腺癌患者复发的方法。根据本发明,所述步骤包括以下步骤:从作为对象的乳腺癌患者收集活检组织,使用RNA提取试剂盒从所述活检组织获得关于多个差异表达基因和表达水平的信息,以及所述多个差异表达基因。通过将表达水平信息应用于预先训练的免疫基因差异表达模型来预测受试者的复发可能性。如上所述,根据本发明,用于乳腺癌患者的复发预测方法提取乳腺癌中免疫相关基因之间差异表达的基因,并且可以通过提取的差异表达基因从少量样本的数据中预测复发。可以构建免疫基因差异表达模型。因此,可以以低成本高精度地预测乳腺癌患者的复发。

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