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Method of manufacturing breast cancer animal model and uses thereof

机译:乳腺癌动物模型的制造方法及其用途

摘要

The present invention relates to a method of manufacturing an animal model of breast cancer, including the step of knocking out the ARL6IP4 gene, an animal model of breast cancer prepared by the method, and a method of screening a drug candidate for treating breast cancer using the animal model of breast cancer. Since the breast cancer animal model manufactured by the method of the present invention progresses rapidly in the development of breast cancer and lung metastasis, based on the animal model, the breast cancer metastasis characteristics are established to conduct basic research for the development of breast cancer treatment and screening of candidate drugs for breast cancer treatment. It is expected to be useful in clinical studies such as.
机译:本发明涉及一种乳腺癌动物模型的制备方法,包括敲除ARL6IP4基因的步骤,通过该方法制备的乳腺癌动物模型以及使用该方法筛选治疗乳腺癌的候选药物的方法。乳腺癌的动物模型。由于通过本发明的方法制造的乳腺癌动物模型在乳腺癌和肺转移的发展中迅速发展,因此,基于该动物模型,建立了乳腺癌转移特征以进行乳腺癌治疗的发展的基础研究。和筛选用于乳腺癌治疗的候选药物。有望在诸如的临床研究中有用。

著录项

  • 公开/公告号KR20200110557A

    专利类型

  • 公开/公告日2020-09-24

    原文格式PDF

  • 申请/专利权人 국립암센터;동국대학교 산학협력단;

    申请/专利号KR20190029636

  • 发明设计人 이호;박미경;이창훈;

    申请日2019-03-15

  • 分类号A01K67/027;C12N15/10;C12N15/113;C12N15/85;C12N9/22;

  • 国家 KR

  • 入库时间 2022-08-21 11:06:00

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