首页> 外国专利> NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS, SUCH AS LUNG CANCER, INCLUDING NSCLC

NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS, SUCH AS LUNG CANCER, INCLUDING NSCLC

机译:针对多种肿瘤的新型免疫疗法,例如肺癌,包括非小细胞肺癌

摘要

The present invention relates to peptides, nucleic acids and cells for use in immunotherapy methods. In particular, the present invention relates to cancer immunotherapy. In addition, the present invention relates to a tumor-associated cytotoxic T cell (CTL) peptide epitope alone or in combination with other tumor-associated peptides acting as an active pharmaceutical ingredient of a vaccine composition that promotes an anti-tumor immune response. The present invention relates to more than 70 novel peptide sequences derived from HLA type I and HLA type II molecules of human tumor cells and variants thereof that can be used in vaccine compositions required to elicit an anti-tumor immune response.
机译:本发明涉及用于免疫治疗方法的肽,核酸和细胞。特别地,本发明涉及癌症免疫疗法。另外,本发明涉及单独的肿瘤相关的细胞毒性T细胞(CTL)肽表位或与其他肿瘤相关的肽组合用作促进抗肿瘤免疫应答的疫苗组合物的活性药物成分的表位。本发明涉及源自人肿瘤细胞的I型HLA和II型HLA分子的70多种新颖肽序列及其变体,它们可用于引起抗肿瘤免疫应答的疫苗组合物中。

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