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Antibody for inducing brown adipocyte differentiation and composition for preventing or treating metabolic syndromes containing the same
Antibody for inducing brown adipocyte differentiation and composition for preventing or treating metabolic syndromes containing the same
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机译:诱导褐色脂肪细胞分化的抗体和用于预防或治疗代谢综合征的组合物
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摘要
The present invention relates to a brown adipocyte differentiation-inducing antibody and a composition for preventing or treating metabolic diseases comprising the same as an active ingredient.According to the present invention, a novel H3 antibody and an IYD substrate that is an IYD (iodotyrosine deiodinase) agonist are Induces differentiation into brown adipocytes in the bar, which generates heat and consumes energy, thereby exhibiting the effect of treating obesity. In addition, the use of an antibody having a low side effect and a long half-life in the body can compensate for the disadvantages of conventional therapeutic agents and improve the therapeutic effect. Accordingly, the IYD agonist having the above effects can be usefully used as a pharmaceutical composition for preventing or treating metabolic diseases.
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