Method for diagnosis of irritable bowel syndrome using analysis of bacteria metagenome

摘要

The present invention relates to a method for diagnosing hypersensitivity syndrome by analyzing bacterial metagenome, and more particularly, by analyzing bacterial metagenome using a sample derived from a subject, analyzing the increase or decrease in the content of specific bacterial-derived extracellular vesicles. It relates to a method for diagnosing growth syndrome. Extracellular vesicles secreted by the bacteria present in the intestine may be absorbed into the body and directly affect inflammation and intestinal function, and hypersensitivity growth syndrome is difficult to diagnose early because symptoms are difficult to effectively treat, so the present invention Metagenome analysis of extracellular vesicles derived from bacteria using a human-derived sample to predict the risk of developing hypersensitivity syndrome in advance, and early diagnosis and prediction of risk groups of hypersensitivity syndrome can be delayed or developed through appropriate management. It is possible to prevent, and even after the onset of the cause can be diagnosed, through the food or drugs that control the causative factor can increase the treatment effect of hypersensitivity syndrome.