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UDP- UDP-GLUCURONOSYLTRANSFERASE SINGLE NUCLEOTIDE POLYMORPHISM MARKERS AND USE THEREOF
UDP- UDP-GLUCURONOSYLTRANSFERASE SINGLE NUCLEOTIDE POLYMORPHISM MARKERS AND USE THEREOF
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机译:UDP- UDP-葡糖醛酸转移酶单核苷酸多态性标记及其用途
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摘要
The present invention provides a composition for predicting or diagnosing diseases and drug susceptibility associated with an in vivo glucuronidation reaction using a UDP-glucuronosyltransferase (UGT) polymorphic marker, and the disease and drug susceptibility using the same. A prediction and diagnostic method. Glucuronidation reaction-related diseases and drug susceptibility diagnostic method according to the present invention exhibits high accuracy, especially for Asians including Koreans, can be quickly and easily diagnosed, increasing the therapeutic efficiency of the disease and dangerous drugs with side effects This may help determine the dosage of.
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