Recombinant yeast transformant and process for preparing immunoglobulin Fc fragment employing the same

摘要

The present invention is an expression vector comprising a polynucleotide encoding an immunoglobulin Fc fragment derived from human pichia ( pichia)sp. 1) A method for producing an immunoglobulin Fc fragment comprising the transformant introduced into the yeast, and transforming the transformant, and culturing the transformant and recovering an immunoglobulin Fc fragment from the culture. It relates to an immunoglobulin Fc fragment that can be used as a carrier. The transformant of the present invention can solve the problems caused by using E. coli or animal cells as a host in producing an immunoglobulin Fc fragment used as a carrier of a drug, thereby producing a more effective and economical drug. It can be widely used for