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SILICONE GEL ADHESIVE WITH HYDROPHILIC AND ANTIMICROBIAL PROPERTIES

机译:具有亲水和抗菌特性的硅酮胶

摘要

An adhesive composition is provided that includes a crosslinked silicone gel, a hydrophilic component dispersed in the silicone gel, and an antimicrobial agent dispersed in the silicone gel. The present adhesive composition is easily applied to (and removed from) the skin and has desirable hydrophilic and antimicrobial properties. Advantageously, the hydrophilic component in the crosslinked silicone gel is not readily extractable (eg, into a buffer at pH 7). Surprisingly, the combination of the hydrophilic component and the antimicrobial agent in the crosslinked silicone gel can provide a synergistic level of antimicrobial activity.
机译:提供一种粘合剂组合物,其包括交联的硅凝胶,分散在该硅凝胶中的亲水性成分和分散在该硅凝胶中的抗微生物剂。本发明的粘合剂组合物易于施用到皮肤上(和从皮肤上除去),并具有所需的亲水和抗菌性能。有利地,交联的硅凝胶中的亲水性组分不易提取(例如,提取到pH 7的缓冲液中)。出人意料的是,在交联的有机硅凝胶中亲水组分和抗微生物剂的组合可以提供协同水平的抗微生物活性。

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